A small change to a powerful molecular tool — using the CRISPR-Cas13 enzyme, which can detect RNA from viruses and cells — ...

In recent years, the scientific community has made significant strides in the field of gene editing, particularly through the development of the CRISPR (Clustered Regularly Interspaced Short ...

While early research suggested that CRISPR-Cas9 effectors can inhibit the replication of single-stranded RNA viruses with DNA intermediates in mammalian cells, stealth start-up Carver Bioscience has ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA ...

BOSTON--(BUSINESS WIRE)--Carver Biosciences, Inc., a biotech company focused on the development of CRISPR/Cas13 antivirals, today announced the closure of a seed round of funding, led by Khosla ...

CRISPR‐based point‐of‐care diagnostics incorporating Cas9, Cas12, and Cas13 enzymes advanced for SARS‐CoV‐2 detection. Verma MK, Roychowdhury S, Sahu BD, Mishra A, Sethi KK.

Researchers at the Broad Institute of MIT and Harvard (both MA, USA) have designed a Cas13–CRISPR construct that can act as a diagnostic and antiviral. The ‘CARVER’ system, detailed in Molecular Cell, ...

Cas13 is capable of intrinsically targeting host RNA in mammalian cells through mechanisms that were not previously understood. Through transcript-specific mechanisms that are independent of the ...

“Ten years ago, it was super hard to think about targeting individual genes. And now that’s something, with these kinds of CRISPR screens, we can do routinely,” said Neville Sanjana, a geneticist at ...