An international team of researchers has discovered a natural mechanism that protects the heart from heart failure with preserved ejection fraction (HFpEF), a serious condition in need of effective ...

Heart development is a continuous process involving significant remodeling during embryogenesis and neonatal stages. To date, several groups have used single-cell sequencing to characterize the heart ...

A study published today in the journal Developmental Cell uncovers new insights into how the heart forms during the earliest stages of embryonic development. The research, led by scientists at the ...

Please provide your email address to receive an email when new articles are posted on . Incident HF was linked to a decline in acute global cognition and later steep decline in cognitive function.

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists—so far. A new multi-chamber organoid ...

Heart development relies on topologically orchestrated cellular transitions and interactions, many of which remain poorly characterized in humans. Here, we combined unbiased spatial and single-cell ...

Researchers at the Francis Crick Institute have discovered that the heart's own contractions trigger biological signals that guide the formation of a functional beating heart. Their study in zebrafish ...

image: A team at the Technical University of Munich (TUM) has induced stem cells to emulate the development of the human heart. The result is a sort of “mini-heart” known as an organoid. It will ...

The heartbeat is synonymous with life. It's one of the first essential functions to begin during development and to end at death. "The heart is one of the first organs to form and function during ...

In humans, a specialized mRNA translation circuit predetermines the competence for heart formation at an early stage of embryonic development, a research team at the Center for Molecular Medicine ...

Pediatric heart defects are the most common birth defect in the world. One of those affected children is 4-year-old Conor Farrell.

A hole in the heart is a nonmedical term for a type of congenital heart defect. There are many types of holes in the heart, and most are present from birth. Around 1% of babies born in the United ...