Leptin is a cell-signalling hormone vital in the regulation of appetite, food intake and body weight. Studies have shown that an absence of leptin in the body or leptin resistance can lead to ...

All subjects received a medical screening and diagnostic evaluation, including the Diagnostic Interview for Genetic Studies (Nurnberger et al, 1994) (DIGS) and a review of available medical records, ...

Patients with obesity sometimes have leptin resistance, and the "full" feeling does not get through to the brain. The new ...

Leptin is a hormone that is produced in adipocytes and exerts its effects on the brain and several other peripheral tissues. It plays a crucial role in regulating endocrine functions and controlling ...

In a new study, Yale researchers offer insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. Their findings advance knowledge about leptin and weight gain, and ...

Leptin reduces food intake in part by enhancing satiety responses to gastrointestinal signals produced in response to food consumption. Glucagon-like peptide 1 (GLP-1), secreted by the intestine when ...

Twenty years after the hormone leptin was found to regulate metabolism, appetite, and weight through brain cells called neurons, Yale School of Medicine researchers have found that the hormone also ...

Scientists have found that a midgestation increase in the hormone leptin, which most of us associate with appetite suppression, produces problematic blood vessel dysfunction and restriction of the ...