US FDA pushes for new methods to replace animal testing in early drug studies

March 18 (Reuters) - The U.S. Food and Drug Administration on Wednesday issued a draft guidance to help companies reduce ...

The push to end animal testing is gaining steam, but technology can’t fill the gap yet

The FDA has released draft guidance that aims to clear up how drug developers can use alternative testing – but that doesn’t ...

FDA issues guidance on alternatives to animal testing

The U.S. Food and Drug Administration issued a draft guidance on Wednesday to help drug developers validate alternative methods that can be used in place of animal studies during early stages of drug ...
Sierra Sun Times

Humane World for Animals Encouraged as Reforms to Modernize Drug Testing Using Non-Animal Methods Continue at Food and Drug Administration

This is the latest in a series of steps the agency has taken over the past two years to reduce reliance on animal testing. In ...
Sierra Sun Times

NIH Invests $150 Million in Human-Based Research to Reduce Use of Animal Models

March 23, 2026 – National Institutes of Health (NIH) released the following: ...
Healio

FDA efforts to reduce animal testing signal shift toward AI, organ-on-chip study methods

In April 2025, the FDA announced plans to shift biomedical research for monoclonal antibodies and other medications away from ...

Vanda Pharmaceuticals Calls for Stronger FDA Action to Accelerate Shift from Animal Testing to Human-Relevant Methods

Vanda Pharmaceuticals Inc. (Vanda) (Nasdaq: VNDA), a leader in innovative drug development and a vocal advocate for reducing ...

Why AI means animal testing not always needed to trial new medicines

Animal testing for new drugs is being phased out because of advances made in artificial intelligence (AI), the UK’s medicines ...
BioSpace

FDA Blueprint Aims To Cut Regulatory Risk for Alternatives to Animal Testing

Draft guidance, issued by the FDA last week, could remove ambiguity and uncertainty that may have so far limited uptake of ...
Morning Overview on MSN

Effort to end animal testing grows, but alternatives still fall short

Federal regulators in the United States are pushing harder than ever to reduce and eventually replace animal testing in drug ...
Applied Clinical Trials Online

FDA Issues Draft Guidance to Validate Non-Animal Testing Methods in Drug Development

The FDA has released a draft guidance outlining how drug developers can validate new approach methodologies (NAMs) as ...
Los Angeles Times

Letters to the Editor: Until new methods are fully validated, we still must consider animal testing

To the editor: While only a small percentage of ALS cases are associated with the SOD1 gene mutation, the SOD1 mouse model actively contributed to the development of two key FDA-approved ALS drugs, ...