Neutralization assays constitute the definitive means to quantify the functional capacity of antibodies to inhibit SARS-CoV-2 entry into host cells. By assessing how serum or monoclonal antibodies ...
Understanding which viral variants evade neutralization is crucial for improving antibody-based treatments, especially with rapidly evolving viruses like SARS-CoV-2. Yet, conventional assays are labor ...
Epitope mapping was performed using structural analysis to classify antibodies according to their binding sites on the receptor-binding domain (RBD). The neutralization activity of representative ...
A research team has successfully developed the world's first nasal organoid-based SARS-CoV-2 neutralizing antibody evaluation platform. The platform uses respiratory organoids that adequately model ...
The COVID-19 pandemic renewed interest in vaccinations, and scientific advancements abound. Developers are continually working to create vaccines that elicit targeted, strong, and long-lasting immune ...
Inherently vulnerable to viral contamination, biologics rely on animal- or human-derived starting materials and complex manufacturing processes. Albeit rare, viral contamination incidents are ...
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